hrp0082p3-d1-816 | Growth | ESPE2014

The Level and Conformation of Blood Plasma Carotenoids in Girls with Turner Syndrome After 1 Year of GH Therapy

Pankratova Maria , Faassen Maria , Kovalenko Svetlana , Yusipovich Alexander , Baizhumanov Adil , Shiryaeva Tatyana , Maksimov Georgy

Background: The concentration and conformation of carotenoids and blood plasma in girls with Turner syndrome (TS) were observed.Objective and hypotheses: The level and conformation of blood plasma carotenoids could be used as markers of overall condition of patients. The obtained data was compared with the parameters of antioxidant status before and after 1 year of GH therapy.Method: 12 prepubertal girls (median 13.2 years) with TS...

hrp0082p2-d2-426 | Growth Hormone (1) | ESPE2014

The Level and Conformation of Blood Plasma Carotenoids in GH Deficient Children After 1 Year of GH Therapy

Faassen Maria , Pankratova Maria , Shiryaeva Tatyana , Nagaeva Elena , Peterkova Valentina , Kovalenko Svetlana , Baizhumanov Adil , Parshina Evgenia , Yusipovich Alexander , Maksimov Georgy

Background: Epidemiologic studies have shown strong associations between high carotenoids levels and reduced risk of developing various forms of cancer, cardiovascular system diseases, etc.Objective and hypotheses: Carotenoids are hydrophobic substances and are contained in blood in lipoprotein particles. Their conformation depends on their molecular environment. By evaluating the conformation of carotenoids we can obtain various information about the li...